Assay Detail
Functional
CHEMBL4357188
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Antiproliferative activity against human HeLa cells assessed as reduction in cell viability in presence of cisplatin after 48 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Novel Cell-Penetrating Peptide Conjugated Proteasome Inhibitors: Anticancer and Antifungal Investigations.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.83 | 5.94 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4581126 | — | — | 1 | 5.94 |
| CHEMBL4587036 | — | — | 1 | 5.72 |
| CHEMBL4460318 | — | — | 1 | - |
| CHEMBL4447701 | — | — | 1 | - |
| CHEMBL4453814 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4581126 | — | IC50 | = | 1160.0 | nM | 5.94 |
| CHEMBL4587036 | — | IC50 | = | 1900.0 | nM | 5.72 |
| CHEMBL4460318 | — | IC50 | - | — | - | |
| CHEMBL4447701 | — | IC50 | - | — | - | |
| CHEMBL4453814 | — | IC50 | - | — | - |