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Assay Detail

CHEMBL4357310

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to bovine carbonic anhydrase 2
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Bos taurus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Carbonic anhydrase 2 (CHEMBL2283)
Type SINGLE PROTEIN
Organism Bos taurus

Publication

Kinetic Target-Guided Synthesis: Reaching the Age of Maturity.
Bosc D, Camberlein V, Gealageas R, Castillo-Aguilera O, Deprez B, Deprez-Poulain R.
J Med Chem (2020) 63 : 3817 -3833
PubMed 31820982 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 8.37 9.30

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4450233 1 9.30
CHEMBL272881 1 7.43

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4450233 Kd = 0.5 nM 9.30
CHEMBL272881 Kd = 37.0 nM 7.43