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Assay Detail

CHEMBL4357690

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Binding
Binding affinity to Ostrinia furnacalis chitinase h catalytic domain overexpressed in Pichia pastoris by isothermal titration calorimetry
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Ostrinia furnacalis
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Chitinase (CHEMBL4523313)
Type SINGLE PROTEIN
Organism Ostrinia furnacalis

Publication

A Series of Compounds Bearing a Dipyrido-Pyrimidine Scaffold Acting as Novel Human and Insect Pest Chitinase Inhibitors.
Jiang X, Kumar A, Motomura Y, Liu T, Zhou Y, Moro K, Zhang KYJ, Yang Q.
J Med Chem (2020) 63 : 987 -1001
PubMed 31928006 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 1 7.07 7.07

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1583158 1 7.07

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1583158 Kd = 85.0 nM 7.07