Assay Detail
Binding
CHEMBL4358378
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Displacement of [125I]Ang II from AT2 receptor in in pig uterus membranes
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Sus scrofa |
| Tissue | Uterus |
| Subcellular | Membranes |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
The Other Angiotensin II Receptor: AT2R as a Therapeutic Target.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 8.98 | 9.40 |
| IC50 | 1 | 7.00 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL189568 | BULOXIBUTID | 0.5 | 1 | 9.40 |
| CHEMBL288174 | — | — | 1 | 8.55 |
| CHEMBL290214 | — | — | 1 | 7.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL189568 | BULOXIBUTID | Ki | = | 0.4 | nM | 9.40 |
| CHEMBL288174 | — | Ki | = | 2.8 | nM | 8.55 |
| CHEMBL290214 | — | IC50 | = | 101.0 | nM | 7.00 |