Assay Detail
Binding
CHEMBL4358380
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human AT1 receptor
3
Total Activities
3
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
The Other Angiotensin II Receptor: AT2R as a Therapeutic Target.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.69 | 7.41 |
| Ki | 1 | 7.92 | 7.92 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL321820 | — | — | 1 | 7.92 |
| CHEMBL34124 | OLODANRIGAN | 2.0 | 1 | 7.41 |
| CHEMBL4448705 | — | — | 1 | 5.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL321820 | — | Ki | = | 12.0 | nM | 7.92 |
| CHEMBL34124 | OLODANRIGAN | IC50 | = | 39.0 | nM | 7.41 |
| CHEMBL4448705 | — | IC50 | = | 1100.0 | nM | 5.96 |