Assay Detail
Functional
CHEMBL4360798
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Antiviral activity against Rhinovirus
4
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Enterovirus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Back to the future: Advances in development of broad-spectrum capsid-binding inhibitors of enteroviruses.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 6.50 | 8.00 |
| IC50 | 2 | 8.20 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL283639 | DISOXARIL | 2.0 | 1 | 8.40 |
| CHEMBL4530977 | — | — | 1 | 8.00 |
| CHEMBL57071 | — | — | 1 | 8.00 |
| CHEMBL4563870 | — | — | 1 | 4.99 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL283639 | DISOXARIL | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL4530977 | — | EC50 | = | 10.0 | nM | 8.00 |
| CHEMBL57071 | — | IC50 | = | 10.0 | nM | 8.00 |
| CHEMBL4563870 | — | EC50 | = | 10200.0 | nM | 4.99 |