Assay Detail
Functional
CHEMBL4362071
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human CL141 cells harboring wild-type EGFR incubated for 72 hrs by SRB assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure-guided development of purine amide, hydroxamate, and amidoxime for the inhibition of non-small cell lung cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.47 | 6.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4443725 | — | — | 1 | 6.50 |
| CHEMBL4515196 | — | — | 1 | 6.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4443725 | — | IC50 | = | 320.0 | nM | 6.50 |
| CHEMBL4515196 | — | IC50 | = | 370.0 | nM | 6.43 |