Assay Detail
Functional
CHEMBL4362073
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antiproliferative activity against human CL25 cells harboring mutated EGFR incubated for 72 hrs by SRB assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Structure-guided development of purine amide, hydroxamate, and amidoxime for the inhibition of non-small cell lung cancer.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.35 | 6.36 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4515196 | — | — | 1 | 6.36 |
| CHEMBL4443725 | — | — | 1 | 6.33 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4515196 | — | IC50 | = | 440.0 | nM | 6.36 |
| CHEMBL4443725 | — | IC50 | = | 470.0 | nM | 6.33 |