Assay Detail
Functional
CHEMBL4362177
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Antimycobacterial activity against Mycobacterium marinum NCTC 2275 by resazurin dye based fluorimetric assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mycobacterium marinum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
The synthesis and in vitro biological evaluation of novel fluorinated tetrahydrobenzo[j]phenanthridine-7,12-diones against Mycobacterium tuberculosis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.37 | 6.85 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL32 | MOXIFLOXACIN | 4.0 | 1 | 6.85 |
| CHEMBL4561092 | — | — | 1 | 5.49 |
| CHEMBL4521723 | — | — | 1 | 5.48 |
| CHEMBL4458310 | — | — | 1 | 5.30 |
| CHEMBL4455926 | — | — | 1 | 5.11 |
| CHEMBL4456278 | — | — | 1 | 5.05 |
| CHEMBL4443260 | — | — | 1 | 4.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL32 | MOXIFLOXACIN | IC50 | = | 140.0 | nM | 6.85 |
| CHEMBL4561092 | — | IC50 | = | 3220.0 | nM | 5.49 |
| CHEMBL4521723 | — | IC50 | = | 3300.0 | nM | 5.48 |
| CHEMBL4458310 | — | IC50 | = | 5040.0 | nM | 5.30 |
| CHEMBL4455926 | — | IC50 | = | 7730.0 | nM | 5.11 |
| CHEMBL4456278 | — | IC50 | = | 9000.0 | nM | 5.05 |
| CHEMBL4443260 | — | IC50 | = | 45490.0 | nM | 4.34 |