Assay Detail
Functional
CHEMBL4362179
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antimycobacterial activity against Mycobacterium bovis BCG ATCC 35737 by resazurin dye based fluorimetric assay
7
Total Activities
7
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mycobacterium tuberculosis variant bovis BCG |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Mycobacterium tuberculosis variant bovis BCG (CHEMBL615052) ↗| Type | ORGANISM |
| Organism | Mycobacterium tuberculosis variant bovis BCG |
Publication
The synthesis and in vitro biological evaluation of novel fluorinated tetrahydrobenzo[j]phenanthridine-7,12-diones against Mycobacterium tuberculosis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 5.34 | 7.52 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL32 | MOXIFLOXACIN | 4.0 | 1 | 7.52 |
| CHEMBL4521723 | — | — | 1 | 5.30 |
| CHEMBL4455926 | — | — | 1 | 5.10 |
| CHEMBL4458310 | — | — | 1 | 4.99 |
| CHEMBL4443260 | — | — | 1 | 4.90 |
| CHEMBL4456278 | — | — | 1 | 4.83 |
| CHEMBL4561092 | — | — | 1 | 4.76 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL32 | MOXIFLOXACIN | IC50 | = | 30.0 | nM | 7.52 |
| CHEMBL4521723 | — | IC50 | = | 5030.0 | nM | 5.30 |
| CHEMBL4455926 | — | IC50 | = | 7900.0 | nM | 5.10 |
| CHEMBL4458310 | — | IC50 | = | 10350.0 | nM | 4.99 |
| CHEMBL4443260 | — | IC50 | = | 12530.0 | nM | 4.90 |
| CHEMBL4456278 | — | IC50 | = | 14950.0 | nM | 4.83 |
| CHEMBL4561092 | — | IC50 | = | 17390.0 | nM | 4.76 |