Assay Detail
Functional
CHEMBL4362882
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Antiviral activity against Influenza A virus A/WSN/33 assessed as inhibition of virus-induced cytopathic effect after 40 hrs by Celltiter-Glo assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Influenza A virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Design, synthesis of oleanolic acid-saccharide conjugates using click chemistry methodology and study of their anti-influenza activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.03 | 5.74 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1200340 | OSELTAMIVIR PHOSPHATE | 4.0 | 1 | 5.74 |
| CHEMBL4539433 | — | — | 1 | 5.26 |
| CHEMBL4465798 | — | — | 1 | 5.14 |
| CHEMBL4549206 | — | — | 1 | 4.89 |
| CHEMBL168 | OLEANOLIC_ACID | — | 1 | 4.14 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1200340 | OSELTAMIVIR PHOSPHATE | IC50 | = | 1820.0 | nM | 5.74 |
| CHEMBL4539433 | — | IC50 | = | 5470.0 | nM | 5.26 |
| CHEMBL4465798 | — | IC50 | = | 7220.0 | nM | 5.14 |
| CHEMBL4549206 | — | IC50 | = | 12930.0 | nM | 4.89 |
| CHEMBL168 | OLEANOLIC_ACID | IC50 | = | 72200.0 | nM | 4.14 |