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Assay Detail

CHEMBL4362887

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Influenza B virus B/Massachusetts/2/2012(BV) infected in MDCK cells assessed as inhibition of virus-induced cytopathic effect after 40 hrs by Celltiter-Glo assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Influenza B virus
Confidence 1 — Organism
Curated By Autocuration

Target

Influenza B virus (CHEMBL613129)
Type ORGANISM
Organism Influenza B virus

Publication

Design, synthesis of oleanolic acid-saccharide conjugates using click chemistry methodology and study of their anti-influenza activity.
Su Y, Meng L, Sun J, Li W, Shao L, Chen K, Zhou D, Yang F, Yu F.
Eur J Med Chem (2019) 182 : 111622 -111622
PubMed 31425909 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 4.94 4.94

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4539433 1 4.94
CHEMBL1200340 OSELTAMIVIR PHOSPHATE 4.0 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4539433 IC50 = 11510.0 nM 4.94
CHEMBL1200340 OSELTAMIVIR PHOSPHATE IC50 > 100000.0 nM -