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Assay Detail

CHEMBL4364465

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human MDA-MB-231 cells
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type MDA-MB-231
Confidence 1 — Organism
Curated By Autocuration

Target

MDA-MB-231 (CHEMBL400)
Type CELL-LINE
Organism Homo sapiens

Publication

Developments in the anticancer activity of structurally modified curcumin: An up-to-date review.
Rodrigues FC, Anil Kumar NV, Thakur G.
Eur J Med Chem (2019) 177 : 76 -104
PubMed 31129455 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 2 5.20 5.82

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL557311 1 5.82
CHEMBL140 CURCUMIN 3.0 1 4.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL557311 IC50 = 1520.0 nM 5.82
CHEMBL140 CURCUMIN IC50 = 26500.0 nM 4.58