Assay Detail
Functional
CHEMBL4364494
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Cytotoxicity against human HepG2 Cells
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HepG2 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Developments in the anticancer activity of structurally modified curcumin: An up-to-date review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 5.17 | 6.24 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 6.24 |
| CHEMBL4435732 | — | — | 1 | 5.26 |
| CHEMBL4517144 | — | — | 1 | 4.73 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 4.43 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 570.0 | nM | 6.24 |
| CHEMBL4435732 | — | IC50 | = | 5520.0 | nM | 5.26 |
| CHEMBL4517144 | — | IC50 | = | 18610.0 | nM | 4.73 |
| CHEMBL140 | CURCUMIN | IC50 | = | 36770.0 | nM | 4.43 |