Assay Detail
Functional
CHEMBL4364495
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Cytotoxicity against human HeLa Cells
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HeLa |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Developments in the anticancer activity of structurally modified curcumin: An up-to-date review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.08 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 5.70 |
| CHEMBL4517144 | — | — | 1 | 4.90 |
| CHEMBL557311 | — | — | 1 | 4.85 |
| CHEMBL140 | CURCUMIN | 3.0 | 1 | 4.85 |
| CHEMBL4435732 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 2020.0 | nM | 5.70 |
| CHEMBL4517144 | — | IC50 | = | 12470.0 | nM | 4.90 |
| CHEMBL557311 | — | IC50 | = | 14030.0 | nM | 4.85 |
| CHEMBL140 | CURCUMIN | IC50 | = | 14030.0 | nM | 4.85 |
| CHEMBL4435732 | — | IC50 | > | 10000.0 | nM | - |