Assay Detail
Binding
CHEMBL4367182
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human farnesyl diphosphate synthase in expressed in Escherichia coli using GPP and [1-14C]IPP as substrate incubated for 15 min by scintillation counting
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Benzylideneacetone Derivatives Inhibit Osteoclastogenesis and Activate Osteoblastogenesis Independently Based on Specific Structure-Activity Relationship.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.34 | 6.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL675 | ALENDRONATE SODIUM | 4.0 | 1 | 6.34 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL675 | ALENDRONATE SODIUM | IC50 | = | 460.0 | nM | 6.34 |