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Assay Detail

CHEMBL4367536

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Binding
Binding affinity to C-terminal 6His-tagged BTN3A1 full interaction domain (unknown origin) expressed in Escherichia coli BL21 (DE) by isothermal calorimetric titration method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Butyrophilin subfamily 3 member A1 (CHEMBL4105758)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Probing the Ligand-Binding Pocket of BTN3A1.
Poe MM, Agabiti SS, Liu C, Li V, Teske KA, Hsiao CC, Wiemer AJ.
J Med Chem (2019) 62 : 6814 -6823
PubMed 31268699 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Kd 2 5.81 5.81

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL145233 1 5.81
CHEMBL4116247 1 -

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL145233 Kd = 1540.0 nM 5.81
CHEMBL4116247 Kd = 111000.0 nM -