Assay Detail
Functional
CHEMBL4367799
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Antileishmanial activity against miltefosine and paromomycin resistant promastigote stage of Leishmania infantum LEM2126 isolate measured after 72 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania infantum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
4-Aminoquinoline-based compounds as antileishmanial agents that inhibit the energy metabolism of Leishmania.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.68 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL267345 | AMPHOTERICIN B | 4.0 | 1 | 7.00 |
| CHEMBL4217754 | — | — | 1 | 6.35 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL267345 | AMPHOTERICIN B | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL4217754 | — | IC50 | = | 450.0 | nM | 6.35 |