Assay Detail
Functional
CHEMBL4367809
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Potentiation of amphotericin B induced antileishmanial activity against promastigote stage of Leishmania infantum MHOM/TN/80/IPT1 at 0.25 uM measured after 72 hrs by MTT assay (Rvb = 0.09 +/- 0.01 microM)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania infantum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
4-Aminoquinoline-based compounds as antileishmanial agents that inhibit the energy metabolism of Leishmania.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.16 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4217754 | — | — | 1 | 7.16 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4217754 | — | IC50 | = | 70.0 | nM | 7.16 |