Assay Detail
Functional
CHEMBL4367825
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Potentiation of miltefosine induced antileishmanial activity against promastigote stage of Leishmania infantum MHOM/TN/80/IPT1 at 0.1 uM measured after 72 hrs by MTT assay (Rvb = 1.43 +/- 0.15 microM)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Leishmania infantum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
4-Aminoquinoline-based compounds as antileishmanial agents that inhibit the energy metabolism of Leishmania.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.02 | 6.02 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4217754 | — | — | 1 | 6.02 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4217754 | — | IC50 | = | 960.0 | nM | 6.02 |