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Assay Detail

CHEMBL4368521

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to human 5HT2A receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

5-hydroxytryptamine receptor 2A (CHEMBL224)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Design, synthesis and evaluation of activity and pharmacokinetic profile of new derivatives of xanthone and piperazine in the central nervous system.
Żelaszczyk D, Jakubczyk M, Pytka K, Rapacz A, Walczak M, Janiszewska P, Pańczyk K, Żmudzki P, Słoczyńska K, Marona H, Waszkielewicz AM.
Bioorg Med Chem Lett (2019) 29 : 126679 -126679
PubMed 31537425 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.09 8.09

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL654 MIRTAZAPINE 4.0 1 8.09

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL654 MIRTAZAPINE Ki = 8.2 nM 8.09