Assay Detail

CHEMBL4369162

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding

Displacement of [3H]DPCPX from pig A1 receptor

ChEMBL ↗

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Target

Unchecked (CHEMBL612545) ↗

Open DB target context

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Unchecked (CHEMBL612545) is the working anchor for this assay review. Loading the live Open DB target snapshot…

Primary target Unchecked

CHEMBL612545

Anchored from Assay target.

Protein identity Unchecked

Disease frame Disease evidence pending

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Review focus Open DB context pending

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Total Activities

Compounds Tested

Activity Types

Assay Parameters

Assay Information

Assay Type	Binding
Organism	Sus scrofa
Confidence	0 — Uncurated / Unknown
Curated By	Autocuration

Target

Unchecked (CHEMBL612545) ↗

Type

UNCHECKED

Publication

Structure activity relationship of 2-arylalkynyl-adenine derivatives as human A<sub>3</sub> adenosine receptor antagonists.

Yu J, Mannes P, Jung YH, Ciancetta A, Bitant A, Lieberman DI, Khaznadar S, Auchampach JA, Gao ZG, Jacobson KA.
Medchemcomm (2018) 9 : 1920 -1932
PubMed 30568760 · DOI

Activity Statistics

Type	Count	Avg pChEMBL	Best pChEMBL
Ki	1	8.19	8.19

Compounds Tested

Compound	Name	Phase	Activities	Best pChEMBL
CHEMBL392149	TECADENOSON	2.0	1	8.19

Activity Data

Compound	Name	Type	Rel.	Value	Units	pChEMBL
CHEMBL392149	TECADENOSON	Ki	=	6.5	nM	8.19