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Assay Detail

CHEMBL4369218

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Binding
Binding affinity to human SST4 receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Somatostatin receptor type 4 (CHEMBL1853)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery of a 3,4,5-trisubstituted-1,2,4-triazole agonist with high affinity and selectivity at the somatostatin subtype-4 (sst<sub>4</sub>) receptor.
Daryaei I, Sandoval K, Witt K, Kontoyianni M, Michael Crider A.
Medchemcomm (2018) 9 : 2083 -2090
PubMed 30746066 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 7.18 7.18

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL1680 OCTREOTIDE 4.0 1 7.18

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL1680 OCTREOTIDE Ki = 66.0 nM 7.18