Assay Detail
Binding
CHEMBL4369696
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Agonist activity at mGlu8 (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Progress toward allosteric ligands of metabotropic glutamate 7 (mGlu7) receptor: 2008-present.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 5.72 | 6.05 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4446107 | — | — | 1 | 6.05 |
| CHEMBL4160748 | — | — | 1 | 5.58 |
| CHEMBL4168668 | — | — | 1 | 5.54 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4446107 | — | EC50 | = | 890.0 | nM | 6.05 |
| CHEMBL4160748 | — | EC50 | = | 2600.0 | nM | 5.58 |
| CHEMBL4168668 | — | EC50 | = | 2900.0 | nM | 5.54 |