Assay Detail
Binding
CHEMBL4369752
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Mixed-type inhibition of mushroom tyrosinase using L-dopa as substrate preincubated for 5 mins followed by substrate addition and measured for 3 mins
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Thiosemicarbazones with tyrosinase inhibitory activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 1 | 6.03 | 6.03 |
| Kis | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL243185 | PHENYLTHIOSEMICARBAZONE | — | 2 | 6.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL243185 | PHENYLTHIOSEMICARBAZONE | Ki | = | 930.0 | nM | 6.03 |
| CHEMBL243185 | PHENYLTHIOSEMICARBAZONE | Kis | = | 93.0 | uM | - |