Assay Detail
Binding
CHEMBL4369754
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Inhibition of mushroom tyrosinase diphenolase activity using L-dopa as substrate after 10 mins by spectrophotometric analysis
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Agaricus bisporus |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Thiosemicarbazones with tyrosinase inhibitory activity.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.50 | 5.58 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL398206 | — | — | 1 | 5.58 |
| CHEMBL242113 | — | — | 1 | 5.42 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL398206 | — | IC50 | = | 2620.0 | nM | 5.58 |
| CHEMBL242113 | — | IC50 | = | 3800.0 | nM | 5.42 |