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Assay Detail

CHEMBL4369759

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Mixed-type inhibition of mushroom tyrosinase by Lineweaver-Burk plot analysis
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Agaricus bisporus
Confidence 9 — Direct single protein target
Curated By Autocuration

Target

Tyrosinase (CHEMBL3318)
Type SINGLE PROTEIN
Organism Agaricus bisporus

Publication

Thiosemicarbazones with tyrosinase inhibitory activity.
Hałdys K, Latajka R.
Medchemcomm (2019) 10 : 378 -389
PubMed 31015905 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 5.90 5.90
Kis 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL391982 2 5.90

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL391982 Ki = 1250.0 nM 5.90
CHEMBL391982 Kis = 2.49 uM -