Assay Detail
Binding
CHEMBL4369795
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to Nurr1 (unknown origin) by 1H-STD-NMR spectroscopy
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Nuclear receptor subfamily 4 group A member 2 (CHEMBL5002) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Ligand-Based Fluorine NMR Screening: Principles and Applications in Drug Discovery Projects.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 2 | 4.35 | 4.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL60796 | DESMETHEYLASTEMIZOLE | — | 1 | 4.70 |
| CHEMBL61301 | TECASTEMIZOLE | 2.0 | 1 | 4.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL60796 | DESMETHEYLASTEMIZOLE | Kd | = | 20000.0 | nM | 4.70 |
| CHEMBL61301 | TECASTEMIZOLE | Kd | = | 100000.0 | nM | 4.00 |