Assay Detail
Binding
CHEMBL4369936
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Inhibition of TSPO (unknown origin)
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Design and in Vivo Characterization of A<sub>1</sub> Adenosine Receptor Agonists in the Native Ribose and Conformationally Constrained (N)-Methanocarba Series.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 6 | 5.57 | 5.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4554295 | — | — | 1 | 5.70 |
| CHEMBL4471712 | — | — | 1 | 5.62 |
| CHEMBL3955519 | — | — | 1 | 5.60 |
| CHEMBL4522864 | — | — | 1 | 5.54 |
| CHEMBL4470080 | — | — | 1 | 5.53 |
| CHEMBL4439013 | — | — | 1 | 5.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4554295 | — | Ki | = | 2020.0 | nM | 5.70 |
| CHEMBL4471712 | — | Ki | = | 2380.0 | nM | 5.62 |
| CHEMBL3955519 | — | Ki | = | 2500.0 | nM | 5.60 |
| CHEMBL4522864 | — | Ki | = | 2890.0 | nM | 5.54 |
| CHEMBL4470080 | — | Ki | = | 2930.0 | nM | 5.53 |
| CHEMBL4439013 | — | Ki | = | 3980.0 | nM | 5.40 |