Assay Detail
Binding
CHEMBL4370205
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Inhibition of human GLO1
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Metal-Binding Pharmacophore Library Yields the Discovery of a Glyoxalase 1 Inhibitor.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 3 | 7.48 | 7.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL2203964 | — | — | 1 | 7.96 |
| CHEMBL128935 | — | — | 1 | 7.85 |
| CHEMBL1234300 | — | — | 1 | 6.64 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL2203964 | — | Ki | = | 11.0 | nM | 7.96 |
| CHEMBL128935 | — | Ki | = | 14.0 | nM | 7.85 |
| CHEMBL1234300 | — | Ki | = | 230.0 | nM | 6.64 |