Assay Detail
Binding
CHEMBL4370404
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human HDAC6 using RHKKAc fluorogenic peptide substrate
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Synthesis and Biological Investigation of Phenothiazine-Based Benzhydroxamic Acids as Selective Histone Deacetylase 6 Inhibitors.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.11 | 8.40 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL356769 | TUBACIN | — | 1 | 8.40 |
| CHEMBL2018302 | TUBASTATIN A | — | 1 | 7.82 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL356769 | TUBACIN | IC50 | = | 4.0 | nM | 8.40 |
| CHEMBL2018302 | TUBASTATIN A | IC50 | = | 15.0 | nM | 7.82 |