Assay Detail
Binding
CHEMBL4370677
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant PIM1 (unknown origin) expressed in Escherichia coli after 60 mins by ELISA
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Serine/threonine-protein kinase pim-1 (CHEMBL2147) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
A review on flavones targeting serine/threonine protein kinases for potential anticancer drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 6.09 | 6.47 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL413552 | QUERCETAGETIN | — | 1 | 6.47 |
| CHEMBL247484 | TRICETIN | — | 1 | 6.19 |
| CHEMBL164 | MYRICETIN | — | 1 | 6.11 |
| CHEMBL293776 | HISPIDULIN | — | 1 | 5.57 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL413552 | QUERCETAGETIN | IC50 | = | 340.0 | nM | 6.47 |
| CHEMBL247484 | TRICETIN | IC50 | = | 650.0 | nM | 6.19 |
| CHEMBL164 | MYRICETIN | IC50 | = | 780.0 | nM | 6.11 |
| CHEMBL293776 | HISPIDULIN | IC50 | = | 2710.0 | nM | 5.57 |