Assay Detail
Binding
CHEMBL4370705
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human CDK4
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
A review on flavones targeting serine/threonine protein kinases for potential anticancer drugs.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.65 | 7.65 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4079206 | — | — | 1 | 7.65 |
| CHEMBL3905910 | VORUCICLIB | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4079206 | — | IC50 | = | 22.5 | nM | 7.65 |
| CHEMBL3905910 | VORUCICLIB | IC50 | < | 100.0 | nM | - |