Assay Detail
Binding
CHEMBL4371518
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Agonist activity at human AT1 receptor assessed as increase in beta-arrestin recruitment by chemiluminescent assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Biased Ligands of G Protein-Coupled Receptors (GPCRs): Structure-Functional Selectivity Relationships (SFSRs) and Therapeutic Potential.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 2 | 7.57 | 7.77 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4542269 | — | — | 1 | 7.77 |
| CHEMBL4438122 | — | — | 1 | 7.36 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4542269 | — | EC50 | = | 17.0 | nM | 7.77 |
| CHEMBL4438122 | — | EC50 | = | 44.0 | nM | 7.36 |