Assay Detail
Functional
CHEMBL4373585
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Cytotoxicity against human CEM/ADR5000 cells assessed as reduction in cell viability after 24 hrs by MTT assay
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | ADR5000 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bifunctional Duocarmycin Analogues as Inhibitors of Protein Tyrosine Kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 8.16 | 8.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4465918 | — | — | 1 | 8.16 |
| CHEMBL4473548 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4465918 | — | IC50 | = | 6.9 | nM | 8.16 |
| CHEMBL4473548 | — | IC50 | > | 10000.0 | nM | - |