Assay Detail
Binding
CHEMBL4373595
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Inhibition of ADH1 (unknown origin) preincubated for 2 hrs followed by substrate/NAD+ addition
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Bifunctional Duocarmycin Analogues as Inhibitors of Protein Tyrosine Kinases.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 5.80 | 6.34 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4465918 | — | — | 1 | 6.34 |
| CHEMBL4473548 | — | — | 1 | 5.25 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4465918 | — | IC50 | = | 460.0 | nM | 6.34 |
| CHEMBL4473548 | — | IC50 | = | 5600.0 | nM | 5.25 |