Assay Detail
Binding
CHEMBL4374475
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Antagonist activity at MR (unknown origin) by Alpha Screen assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Dissecting the allosteric FXR modulation: a chemical biology approach using guggulsterone as a chemical tool.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 6.50 | 6.50 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL402063 | E-GUGGULSTERONE | — | 1 | 6.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL402063 | E-GUGGULSTERONE | IC50 | = | 320.0 | nM | 6.50 |