Assay Detail
Functional
CHEMBL4376314
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Antimalarial activity against Plasmodium falciparum Dd2 by HRP2 assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Plasmodium falciparum |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Primaquine derivatives: Modifications of the terminal amino group.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 5.11 | 5.11 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4522595 | — | — | 1 | 5.11 |
| CHEMBL4460395 | — | — | 1 | 5.11 |
| CHEMBL4463583 | — | — | 1 | 5.11 |
| CHEMBL4593843 | — | — | 1 | 5.11 |
| CHEMBL4449670 | — | — | 1 | 5.11 |
| CHEMBL4445381 | — | — | 1 | 5.11 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4522595 | — | IC50 | = | 7740.0 | nM | 5.11 |
| CHEMBL4460395 | — | IC50 | = | 7740.0 | nM | 5.11 |
| CHEMBL4463583 | — | IC50 | = | 7740.0 | nM | 5.11 |
| CHEMBL4593843 | — | IC50 | = | 7740.0 | nM | 5.11 |
| CHEMBL4449670 | — | IC50 | = | 7740.0 | nM | 5.11 |
| CHEMBL4445381 | — | IC50 | = | 7740.0 | nM | 5.11 |