Assay Detail
Functional
CHEMBL4376777
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Cytotoxicity against human PANC1 cells assessed as reduction in cell viability incubated for 3 days by tryphan blue dye based assay
7
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | PANC-1 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Reinvestigation of Mycothiazole Reveals the Penta-2,4-dien-1-ol Residue Imparts Picomolar Potency and 8S Configuration.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 7 | 8.13 | 9.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4540502 | — | — | 1 | 9.80 |
| CHEMBL4472212 | — | — | 1 | 8.89 |
| CHEMBL4554059 | — | — | 1 | 5.70 |
| CHEMBL1254306 | — | — | 1 | - |
| CHEMBL4513454 | — | — | 2 | - |
| CHEMBL4582379 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4540502 | — | IC50 | = | 0.16 | nM | 9.80 |
| CHEMBL4472212 | — | IC50 | = | 1.3 | nM | 8.89 |
| CHEMBL4554059 | — | IC50 | = | 2000.0 | nM | 5.70 |
| CHEMBL1254306 | — | IC50 | - | — | - | |
| CHEMBL4513454 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL4513454 | — | IC50 | > | 1000.0 | nM | - |
| CHEMBL4582379 | — | IC50 | > | 1000.0 | nM | - |