Assay Detail
Functional
CHEMBL4376915
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Antiviral activity against Respiratory syncytial virus
9
Total Activities
9
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Respiratory syncytial virus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Target
Respiratory syncytial virus (CHEMBL612679) ↗| Type | ORGANISM |
| Organism | Respiratory syncytial virus |
Publication
State of the Art in Respiratory Syncytial Virus Drug Discovery and Development.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 9 | 8.32 | 9.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4528752 | — | — | 1 | 9.82 |
| CHEMBL4435108 | — | — | 1 | 9.25 |
| CHEMBL4297497 | SISUNATOVIR | 2.0 | 1 | 8.89 |
| CHEMBL4458694 | — | — | 1 | 8.56 |
| CHEMBL4542924 | — | — | 1 | 8.00 |
| CHEMBL4469438 | — | — | 1 | 7.51 |
| CHEMBL4540519 | — | — | 1 | 6.18 |
| CHEMBL4522047 | — | — | 1 | - |
| CHEMBL4475481 | ZELICAPAVIR | 2.0 | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4528752 | — | EC50 | = | 0.15 | nM | 9.82 |
| CHEMBL4435108 | — | EC50 | = | 0.56 | nM | 9.25 |
| CHEMBL4297497 | SISUNATOVIR | EC50 | = | 1.3 | nM | 8.89 |
| CHEMBL4458694 | — | EC50 | = | 2.75 | nM | 8.56 |
| CHEMBL4542924 | — | EC50 | = | 10.0 | nM | 8.00 |
| CHEMBL4469438 | — | EC50 | = | 31.0 | nM | 7.51 |
| CHEMBL4540519 | — | EC50 | = | 660.0 | nM | 6.18 |
| CHEMBL4522047 | — | EC50 | < | 1000.0 | nM | - |
| CHEMBL4475481 | ZELICAPAVIR | EC50 | < | 400.0 | nM | - |