Assay Detail
Binding
CHEMBL4377145
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of human His-tagged PNP assessed as inhibitor constant for enzyme-inhibitor complex formation by measuring reduction in uric acid formation by spectrophotometric method
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Plasmodium Purine Metabolism and Its Inhibition by Nucleoside and Nucleotide Analogues.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Ki | 2 | 9.38 | 9.80 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL475750 | — | — | 1 | 9.80 |
| CHEMBL269864 | ULODESINE | 2.0 | 1 | 8.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL475750 | — | Ki | = | 0.16 | nM | 9.80 |
| CHEMBL269864 | ULODESINE | Ki | = | 1.1 | nM | 8.96 |