Assay Detail
Binding
CHEMBL4378239
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of KDR (unknown origin)
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Vascular endothelial growth factor receptor 2 (CHEMBL279) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Drug Discovery Targeting Anaplastic Lymphoma Kinase (ALK).
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 6.43 | 7.00 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL1779202 | — | — | 1 | 7.00 |
| CHEMBL1738797 | ALECTINIB | 4.0 | 1 | 5.85 |
| CHEMBL1823221 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL1779202 | — | IC50 | = | 100.0 | nM | 7.00 |
| CHEMBL1738797 | ALECTINIB | IC50 | = | 1400.0 | nM | 5.85 |
| CHEMBL1823221 | — | IC50 | > | 5000.0 | nM | - |