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Assay Detail

CHEMBL4378247

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Cytotoxicity against human IMR32 cells
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism Homo sapiens
Cell Type IMR-32
Confidence 1 — Organism
Curated By Autocuration

Target

IMR-32 (CHEMBL614585)
Type CELL-LINE
Organism Homo sapiens

Publication

Drug Discovery Targeting Anaplastic Lymphoma Kinase (ALK).
Kong X, Pan P, Sun H, Xia H, Wang X, Li Y, Hou T.
J Med Chem (2019) 62 : 10927 -10954
PubMed 31419130 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 8.55 8.55

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4203266 1 8.55

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4203266 IC50 = 2.8 nM 8.55