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Assay Detail

CHEMBL4378472

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Inhibition of human GST-tagged BCL-XL deltaC24 mutant using BIMBH3 mutant peptide as substrate by SPR assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Hot-Spots of Mcl-1 Protein.
Denis C, Sopková-de Oliveira Santos J, Bureau R, Voisin-Chiret AS.
J Med Chem (2020) 63 : 928 -943
PubMed 31580668 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 7.96 7.96

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL374309 1 7.96

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL374309 IC50 = 11.0 nM 7.96