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Assay Detail

CHEMBL4378701

Review assay metadata, readout intent, target linkage, and publication context from the same page.

ADMET
Inhibition of adenosine transporter (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type ADMET
Organism Homo sapiens
Confidence 0 — Uncurated / Unknown
Curated By Autocuration

Target

Unchecked (CHEMBL612545)
Type UNCHECKED

Publication

Isolation, Structural Identification, Synthesis, and Pharmacological Profiling of 1,2-<i>trans</i>-Dihydro-1,2-diol Metabolites of the Utrophin Modulator Ezutromid.
Chatzopoulou M, Claridge TDW, Davies KE, Davies SG, Elsey DJ, Emer E, Fletcher AM, Harriman S, Robinson N, Rowley JA, Russell AJ, Tinsley JM, Weaver R, Wilkinson IVL, Willis NJ, Wilson FX, Wynne GM.
J Med Chem (2020) 63 : 2547 -2556
PubMed 31599580 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.41 5.41

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4550375 1 5.41

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4550375 IC50 = 3900.0 nM 5.41