Assay Detail
Binding
CHEMBL4378714
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of recombinant human IDO using L-Trp as substrate incubated for 60 mins
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Small-Molecule Inhibitors of Necroptosis: Current Status and Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 6.96 | 6.96 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL195008 | NECROSTATIN | — | 1 | 6.96 |
| CHEMBL366011 | — | — | 1 | 6.96 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL195008 | NECROSTATIN | IC50 | = | 110.0 | nM | 6.96 |
| CHEMBL366011 | — | IC50 | = | 110.0 | nM | 6.96 |