Assay Detail
Binding
CHEMBL4378753
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Binding affinity to MLKL (unknown origin)
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Homo sapiens |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Target
Mixed lineage kinase domain-like protein (CHEMBL1938217) ↗| Type | SINGLE PROTEIN |
| Organism | Homo sapiens |
Publication
Small-Molecule Inhibitors of Necroptosis: Current Status and Perspectives.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| Kd | 1 | 5.03 | 5.03 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL188381 | GW806742X | — | 1 | 5.03 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL188381 | GW806742X | Kd | = | 9300.0 | nM | 5.03 |