Assay Detail
Binding
CHEMBL4379052
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Inhibition of Mycobacterium phlei DSM-43239 C-terminal ATP-synthase assessed as reduction in luciferase activity incubated for 10 mins in presence of ATP by luminometric method
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Organism | Mycolicibacterium phlei DSM 43239 = CCUG 21000 |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Changing the Rules of TB-Drug Discovery.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 1 | 7.70 | 7.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL376488 | BEDAQUILINE | 4.0 | 1 | 7.70 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL376488 | BEDAQUILINE | IC50 | = | 20.0 | nM | 7.70 |