Assay Detail
Functional
CHEMBL4380852
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Antiproliferative activity against human OCI-LY7 cells assessed as reduction in cell viability incubated for 72 hrs by CCK8 assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | OCI-Ly7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Synthesis and Biological Evaluation of B-Cell Lymphoma 6 Inhibitors of N-Phenyl-4-pyrimidinamine Derivatives Bearing Potent Activities against Tumor Growth.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.89 | 5.79 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL4538610 | — | — | 1 | 5.79 |
| CHEMBL4077392 | — | — | 1 | 4.47 |
| CHEMBL4061302 | — | — | 1 | 4.41 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL4538610 | — | IC50 | = | 1620.0 | nM | 5.79 |
| CHEMBL4077392 | — | IC50 | = | 33900.0 | nM | 4.47 |
| CHEMBL4061302 | — | IC50 | = | 39000.0 | nM | 4.41 |