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Assay Detail

CHEMBL4381661

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Antiviral activity against Dengue virus 2 infected in human BE(2)-C cells assessed as reduction in viral progeny production incubated for 48 hrs by Virus titer assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Organism dengue virus type 2
Confidence 1 — Organism
Curated By Autocuration

Target

dengue virus type 2 (CHEMBL613966)
Type ORGANISM
Organism dengue virus type 2

Publication

Benzenesulfonamide Derivatives as Calcium/Calmodulin-Dependent Protein Kinase Inhibitors and Antiviral Agents against Dengue and Zika Virus Infections.
Chen WC, Simanjuntak Y, Chu LW, Ping YH, Lee YL, Lin YL, Li WS.
J Med Chem (2020) 63 : 1313 -1327
PubMed 31972088 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
EC50 1 5.82 5.82
Activity 1 - -

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL4556306 2 5.82

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL4556306 EC50 = 1520.0 nM 5.82
CHEMBL4556306 Activity - -